Megamentin 375: WHAT IS IT?
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Description of the preparation Megamentin 375
Amoxicillin is a semi-synthetic broad-spectrum antibiotic with activity against many gram-positive and gram-negative microorganisms. At the same time, amoxicillin is susceptible to destruction by β-lactamases, and therefore the spectrum of activity of amoxicillin does not extend to microorganisms that produce this enzyme.
Clavulanic acid, a β-lactamase inhibitor structurally related to penicillins, has the ability to inactivate a wide range of β-lactamases found in penicillin and cephalosporin resistant microorganisms.
Clavulanic acid has sufficient efficacy against plasmid β-lactamases, which most often cause bacterial resistance, and is less effective against chromosomal β-lactamases of type 1 that are not inhibited by clavulanic acid.
The presence of clavulanic acid in Megamentin 375 protects amoxicillin from destruction by enzymes – β-lactamases, which allows to expand the antibacterial spectrum of amoxicillin.
Dosage and administration of Megamentin 375
The dosage regimen is set individually depending on the age, body weight, kidney function of the patient, as well as the severity of the infection.
For optimal absorption and reduce possible side effects from the digestive system, Megamentin 375 is recommended to be taken at the beginning of a meal. The minimum course of antibiotic therapy is 5 days.
Treatment should not continue for more than 14 days without a review of the clinical situation.
1 tablet 250 mg / 125 mg 3 times / day (for infections of mild to moderate severity), or 1 tablet 500 mg / 125 mg 3 times / day, or 1 tablet 875 mg / 125 mg 2 times / day, or 11 ml of a suspension of 400 mg / 57 mg / 5 ml 2 times / day (which is equivalent to 1 tablet of 875 mg / 125 mg).
Side effects of Megamentin 375
Infectious and parasitic diseases: often – candidiasis of the skin and mucous membranes.
From the immune system: very rarely – allergic vasculitis.
From the nervous system: infrequently – dizziness, headache.
From the digestive tract: very often – diarrhea, often – nausea, vomiting; Infrequently – digestive disorders.
Megamentin 375 REVIEWS
The drug is very successful not only among professionals, but also bodybuilders. As a result, you can find reviews about Megamentin 375 online as soon as possible. First of all, athletes note a high power effect on the body and do not recommend the use of Augmentin to novice builders. They also note a good level of drug safety. An equally important factor in choosing one or another steroids is its cost. Admittedly, the price of Intas can be considered low on our website – SportsPeople.US.