Proviron (origo, Germany) (mesterolone)

Category: Post Cycle Therapy (PCT)
Substance: mesterolone
Package: 25 mg/tab. (50 tab.)

The clinical application is associated with the treatment of certain problems of the reproductive system, resulting from low levels of testosterone own! Commonly used for the treatment of decreased libido, impotence and oligospremiya!
Proviron does not stimulate the production of testosterone own, but compensates for its lack of strong androgenic action! Despite its high androgenity, anabolic properties are too weak to be used to increase muscle mass! This is because the muscle tissue Proviron quickly and effectively broke its inactive metabolites, which is characteristic of DHT! Rumors that the weak anabolic activity of the preparation, reduces the effect of other steroids used alongside it should not be taken seriously. Rather Proviron increases the other, parallel steroids used it because it has a strong affinity for binding proteins in the blood as SHBG (hormone binding globulin seh), which allows a large number of other steroids to be his free (active ) form!

Despite the presence of mesterolone significantly reduce some risks associated with hormone replacement therapy with androgens, the intake of PROVIRON must necessarily be preceded by a medical examination to evaluate the correctness of the prescriptive and the possible presence of disorders that can increase the risk of side effects.
Consequently, the mesterolone intake in patients with hypertension, heart disease, family history or history of neoplastic diseases, liver diseases and kidney, epilepsy, esser’s supervised carefully by your doctor, providing the suspension of the therapy immediately following the appearance of the first pathological signs.
L use age prepubere’s future, with particular attention, considering the possible deleterious effects on bone growth and too-rapid development of the male genital organs.
PROVIRON contains lactose, therefore its consumption may be related to the appearance of the side effects of the gastro-intestinal tract in patients with lactose intolerance, enzyme deficiency glucose or lactase deficiency malabsorption/galactose.

Although this steroid is strongly androgenic, the anabolic effect of it is considered too weak for muscle building purposes. This is due to the fact that Proviron is rapidly reduced to inactive metabolites in muscle tissue, a trait also characteristic of dihydrotestosterone. The belief that the weak anabolic nature of this compound indicated a tendency to block the androgen receptor in muscle tissue, thereby reducing the gains of other more potent muscle building steroids, should likewise not be taken seriously. In fact due to its extremely high affinity for plasma binding proteins such as SHBG, Proviron may actually work to increase the activity of other steroids by displacing a higher percentage into a free, unbound state. Among athletes Proviron is primarily used as an anti-estrogen. It is believed to act as an anti-aromatase in the body, preventing or slowing the conversion of steroids into estrogen. The result is somewhat comparable to Arimidex (though less profound), the drug acting to prevent the buildup of estrogen in the body. This is in direct contrast to Nolvadex, which only blocks the ability of estrogen to bind and activate receptors in certain tissues. The anti-aromatization effect is preferred, as it is a more direct and efficient means of dealing with the problem of estrogenic side effects. Another disadvantage of Nolvadex is that if discontinued too early, a rebound effect may occur as high serum estrogen levels are again free to take action. This of course could mean a rapid onset of side effects such as gynecomastia. Most actually prefer to use both Proviron and Nolvadex, especially during strongly estrogenic cycles. With each item attacking estrogen at a different angle, side effects are often greatly reduced.

post ID 193