Semisynthetic tetracycline, a broad-spectrum bacteriostatic antibiotic. Penetrating into the cell, acts on intracellularly located pathogens. It inhibits the synthesis of proteins in a microbial cell, disrupts the connection of transport aminoacyl RNAs with the 30S subunit of the ribosomal membrane.
Absorption is fast and high (about 100%). Reception write does not significantly affect the degree of absorption. It has a high degree of lipid solubility and low affinity for the binding of calcium ions (Ca2 +).
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The average daily dose is 200 mg on the first day (divided into 2 doses – 100 mg 2 times a day), then 100 mg / day. Be sure to drink plenty of water.
Doxycycline side effects
From the nervous system: benign increase in intracranial pressure (loss of appetite, vomiting, headache, swelling of the optic nerve head).
Metabolic Disorder: Anorexia.
On the part of the organs of hearing and the vestibular apparatus: ringing in the ears.
From the side of the organs of vision: blurred vision.
From the digestive system: nausea, constipation or diarrhea, abdominal pain.
Allergic reactions: maculopapular rash, skin itching.
From the cardiovascular system: lowering blood pressure, tachycardia.